Endothelium-dependent and endothelium-independent effects of adenosine diphosphate in renovascular hypertension.

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Endothelium-dependent and endothelium-independent effects of adenosine diphosphate in renovascular hypertension.

Norepinephrine-induced responses in isolated perfused mesenteric vascular bed from normotensive and renovascular hypertensive rats were examined in the presence of adenosine diphosphate (ADP, 2 x 10(-6) M). Responses to norepinephrine were significantly greater in vessels from hypertensive rats. Norepinephrine-induced contractions increased after the removal of endothelium. N omega-Nitro-L-argi...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1992

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.19.2_suppl.ii224